Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia and Metabolic Syndrome|
Results from multiple preclinical and clinical studies indicate that several modifiable, age-related metabolic aberrations (metabolic syndrome, obesity, dyslipidaemia, diabetes) are important determinants in both the development and the progression of benign prostatic hyperplasia-related lower urinary tract symptoms (BPH–LUTS). Metabolic syndrome and its related comorbidities, such as sex steroid alterations and low-grade inflammation, have been related to BPH–LUTS development and progression. [Nat Rev Urol]
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