Organoid Culture Systems for Prostate Epithelial and Cancer Tissue
This protocol describes a strategy for the generation of 3D prostate organoid cultures from healthy mouse and human prostate cells (either bulk or FACS-sorted single luminal and basal cells), metastatic prostate cancer lesions and circulating tumor cells. [Nat Protoc] Abstract
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia and Metabolic Syndrome
Results from multiple preclinical and clinical studies indicate that several modifiable, age-related metabolic aberrations (metabolic syndrome, obesity, dyslipidaemia, diabetes) are important determinants in both the development and the progression of benign prostatic hyperplasia-related lower urinary tract symptoms (BPH–LUTS). Metabolic syndrome and its related comorbidities, such as sex steroid alterations and low-grade inflammation, have been related to BPH–LUTS development and progression. [Nat Rev Urol]
Abstract
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INDUSTRY NEWS
Pathcore Selected by National Cancer Institute to Enable Cancer Informatics Development
Pathcore™ and a team of investigators from the US and Canada have received an award from the National Cancer Institute to develop a pathology informatics platform. This will allow researchers to develop automated cancer detection image analysis tools which can be easily distributed to research and clinical users. [Pathcore™ (Business Wire)] Press Release
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