NUSAP1 Expression Is Upregulated by Loss of RB1 in Prostate Cancer Cells NUSAP1 expression is elevated in the RB1-null DU145 prostate cancer cell line, as opposed to LNCaP and PC-3 cell lines. Furthermore, NUSAP1 expression increases upon knockdown of RB1 in prostate cancer cell lines and decreases after knockdown of E2F1. [Prostate] Abstract
Adiponectin Inhibits VEGF-A in Prostate Cancer Cells
Prostate cancer cell lines examined had all lower levels of adiponectin and adiponectin receptor I, compared to normal healthy prostate tissue. Moreover, overexpression of adiponectin in prostate cancer cells decreased production of vascular endothelial growth factor A (VEGF-A), while adiponectin depletion increased VEGF-A. [Tumor Biol] Abstract
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