Volume 11.22 | Jun 19

Prostate Cell News 11.22 | Jun 19 2020
Prostate Cell News by STEMCELL Technologies
Vol. 11.22 – 19 June, 2020
TOP STORY

AR and ERG Drive the Expression of Prostate Cancer Specific Long Noncoding RNAs

In vitro validations confirmed that androgen receptor and ETS-related gene (ERG) regulated a subset of TPCATs, most notably for EPCART.
[Oncogene]

Abstract

Virtual Conference Exhibition: Organoids
PUBLICATIONSRanked by the impact factor of the journal

Dehydrozingerone, a Curcumin Analog, as a Potential Anti-Prostate Cancer Inhibitor In Vitro and In Vivo

The authors revealed that dehydrozingerone decreased cell proliferation of rat castration-resistant prostate cancer, PLS10 cells, via induction of the cell cycle arrest in the G1 phase in vitro.
[Molecules]

Full Article

Effect of Palmitic Acid on Exosome-Mediated Secretion and Invasive Motility in Prostate Cancer Cells

Palmitic acid decreased the secretion of exosomes in human prostate cancer cells in vitro in a concentration-dependent manner.
[Molecules]

Full Article

Androgens Modify Therapeutic Response to Cabazitaxel in Models of Advanced Prostate Cancer

To examine the impact of androgens on the antitumor effect of cabazitaxel (CBZ), investigators used human prostate cancer cell lines with different sensitivity to androgens and CBZ.
[Prostate]

Abstract

Resveratrol Inhibits the Tumor Migration and Invasion by Upregulating TET1 and Reducing TIMP2/3 Methylation in Prostate Carcinoma Cells

Resveratrol inhibited the migration and invasion of prostate cancer cells, promoted the demethylation of tissue inhibitor of metalloproteinases (TIMP)2 and TIMP3 to upregulate their expressions, and suppressed the expressions of MMP2 and MMP9.
[Prostate]

Abstract

Altered Staining Patterns and Expression Level of Engrailed-2 in Benign Prostatic Hyperplasia and Prostate Cancer Predict Prostatic Disease Progression

Scientists showed that their homemade engrailed-2 (EN2) monoclonal antibody could specifically bind endogenous and exogenous EN2 protein in three different prostate cancer cell lines.
[BMC Cancer]

Full Article

The miR-1908/SRM Regulatory Axis Contributes to Extracellular Vesicle Secretion in Prostate Cancer

Researchers investigated the target genes of miR-1908 by siRNA screening and identified that spermidine synthase was the key regulator of extracellular vesicle secretion in 22Rv1 cells.
[Cancer Science]

Abstract

Urupocidin C: A New Marine Guanidine Alkaloid which Selectively Kills Prostate Cancer Cells via Mitochondria Targeting

Researchers discovered a promising selectivity of both alkaloids for human prostate cancer cells, including highly drug-resistant lines, compared to non-malignant cells.
[Scientific Reports]

Full Article

KLF5 Inhibits STAT3 Activity and Tumor Metastasis in Prostate Cancer by Suppressing IGF1 Transcription Cooperatively with HDAC1

Scientists knocked down KLF5 in prostate cancer cells and found that KLF5 knockdown promoted invasive ability of prostate cancer cells in vitro and in vivo .
[Cell Death & Disease]

Full Article

Explore tools and resources for your return to the lab
REVIEWS

Advanced Prostate Cancer: Treatment Advances and Future Directions

The authors summarize clinical trials leading to recent drug approvals and discuss optimal treatment selection.
[Trends in Cancer]

Abstract

Prostate Carcinogenesis: Inflammatory Storms

Scientists provide updates on recent advances in elucidating prostate carcinogenesis and explore novel therapeutic and prevention strategies harnessing these discoveries.
[Nature Reviews Cancer]

Abstract

INDUSTRY AND POLICY NEWS

Bio-Techne and ZERO – The End of Prostate Cancer Announce Partnership to Fund Education and Awareness Campaigns to Empower Men with Prostate Cancer

Bio-Techne Corporation announced that Exosome Diagnostics has established a new partnership with ZERO – The End of Prostate Cancer.
[Bio-Techne Corporation]

Press Release

US Science Groups Wary of New Senate Bills to Curb Foreign Influences

A bipartisan group of US senators proposed sweeping—and controversial—changes in how the federal government manages academic research in the face of threats from other countries.
[ScienceInsider]

Editorial

FEATURED EVENT

International Society for Stem Cell Research (ISSCR): Advances in Stem Cell Research: From Single Cells to Organs

2020-10-12 – 2020-10-14
Paris, France

> See All Events

JOB OPPORTUNITIES

Postdoctoral Position – Cancer Biology

Berlin School of Integrative Oncology Charité – Berlin, Germany

Postdoctoral Studentship – Magnetic Resonance Guided Radiation Therapy on Prostate Cancer

Universitätsklinikum Tübingen – Tübingen, Germany

Postdoctoral Position – 3D Genome Organization in Prostate Cancer

Karolinska Institutet – Solna, Sweden

Postdoctoral Fellow – Prostate Cancer Research

The Vita-Salute San Raffaele University – Milan, Italy

Postdoctoral Fellow – Cancer Metabolism Research

Augusta University – Augusta, Georgia, United States

Associate Professor – Prostate Disease Research

Uniformed Services University of the Health Sciences – Bethesda, Maryland, United States

Postdoctoral Position – Chaperone-Mediated Autophagy Research in Cancer

Karolinska Institutet – Solna, Sweden

Assistant Professor – Cell Cycle and Cancer Biology

Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States

> See All Jobs

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